Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 12/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615088 | 1.00 | TYMP (0.46) | TYMPPDE2AADORA1NT5E | |
| SCHEMBL8610301 | 0.92 | TYMP (0.52) | TYMPADORA1NT5E | |
| SCHEMBL8611229 | 0.91 | TYMP (0.45) | TYMPPDE2AADORA1NT5E | |
| SCHEMBL8611227 | 0.91 | TYMP (0.45) | TYMPPDE2AADORA1NT5E | |
| SCHEMBL8609957 | 0.90 | TYMP (0.52) | TYMPADORA1NT5E | |
| SCHEMBL8609775 | 0.88 | TYMP (0.48) | TYMPPDE2AADORA1NT5E | |
| SCHEMBL8613331 | 0.88 | TYMP (0.46) | TYMPPDE2AADORA1NT5E | |
| SCHEMBL8610263 | 0.88 | TYMP (0.54) | TYMPADORA1NT5E | |
| SCHEMBL8610259 | 0.88 | TYMP (0.54) | TYMPADORA1NT5E | |
| SCHEMBL8611069 | 0.86 | TYMP (0.62) | TYMPADORA1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |