SCHEMBL8615249

SCHEMBL8615249

CCCCCc1ccc(-c2ccc(OCC)c(F)c2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.47
MAPT P10636 3/20 0.45
RAB9A P51151 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
USP2 O75604 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
HSD11B1 P28845 1/20 0.41
TSHR P16473 1/20 0.41
RARA P10276 2/20 0.41
RARG P13631 1/20 0.41
ESR1 P03372 2/20 0.40
ADRA2A P08913 2/20 0.40
ADORA3 P0DMS8 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8972213 0.99 RARB (0.46) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL9493395 0.99 RARB (0.46) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL9485582 0.99 RARB (0.46) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL9494724 0.97 RARB (0.48) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL9563828 0.97 RARB (0.48) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL9563711 0.97 RARB (0.48) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL9494400 0.97 RARB (0.48) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL11953529 0.95 MPL (0.43) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL12736486 0.95 RARB (0.43) RARBMAPTRAB9AL3MBTL1ALDH1A1
SCHEMBL12740941 0.95 RARB (0.43) RARBMAPTRAB9AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-20230183572-A1 LIQUID CRYSTAL COMPOSITION WITH GOOD FREQUENCY DEPENDENCE AND LIQUID CRYSTAL DISPLAY ELEMENT SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230167362-A1 NEGATIVE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT OR LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MAT CO ITD (CN) 2023-06-01 US disclosed
US-11466211-B2 Liquid crystal composition and liquid crystal display element including the same DIC CORPORATION (JP) 2022-10-11 US disclosed
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2022-05-31 US disclosed
EP-2907864-B2 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THIS COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2022-05-18 EP disclosed
US-20150115200-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DIC CORPORATION (JP) 2015-04-30 US disclosed
EP-2806009-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCORPORATING SAME DIC Corporation (JP) 2014-11-26 EP disclosed
EP-2801600-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCORPORATING SAME DIC Corporation (JP) 2014-11-12 EP disclosed
EP-1599561-B1 ELECTRO-LUMINESCENT DEVICE AS WELL AS METHOD OF ITS PREPARATION MERCK PATENT GMBH (DE) 2007-07-25 EP disclosed
EP-0440082-B1 Method for the conversion of fluorinated aromatic compounds using electrophiles MERCK PATENT GMBH (DE) 1998-04-15 EP disclosed
US-5262556-A Alkylation or hydroxyalkylation by deprotonation MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-11-16 US disclosed
EP-0329752-B1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK PATENT GmbH (DE) 1993-03-17 EP disclosed
EP-0440082-A2 Method for the conversion of fluorinated aromatic compounds using electrophiles MERCK PATENT GmbH (DE) 1991-08-07 EP disclosed
EP-0329752-A1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK PATENT GmbH (DE) 1989-08-30 EP disclosed
WO-1989002425-A1 FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions VAC14, VAPA, SFN RARB 3761/4885MAPT 2156/4885RAB9A 2123/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 RARB 3196/4885MAPT 1064/4885RAB9A 3577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.