⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482727 | 0.76 | — | — | |
| SCHEMBL4843298 | 0.73 | — | — | |
| SCHEMBL9700755 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL10939771 | 0.69 | — | — | |
| SCHEMBL9615298 | 0.69 | ALDH1A1 (0.44) | — | |
| SCHEMBL27537063 | 0.69 | — | — | |
| SCHEMBL17137797 | 0.67 | — | — | |
| SCHEMBL28690249 | 0.67 | — | — | |
| SCHEMBL3787125 | 0.67 | — | — | |
| SCHEMBL11749869 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3486711-A1 | LENS-FORMING MATERIALS COMPRISING PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | Novartis AG (CH) | 2019-05-22 | — | — | EP | disclosed |
| EP-2432821-B1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2017-08-30 | — | — | EP | disclosed |
| EP-2510052-B1 | A SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING | NOVARTIS AG (CH) | 2017-02-08 | — | — | EP | disclosed |
| US-9097839-B2 | Method for making silicone hydrogel contact lenses | NOVARTIS AG (CH) | 2015-08-04 | — | — | US | disclosed |
| US-9066981-B2 | Actinically-crosslinkable siloxane-containing copolymers | NOVARTIS AG (CH) | 2015-06-30 | — | — | US | disclosed |
| US-20140100291-A1 | Actinically-Crosslinkable Siloxane-Containing Copolymers | NOVARTIS AG (CH) | 2014-04-10 | — | — | US | disclosed |
| US-8642712-B2 | Actinically-crosslinkable siloxane-containing copolymers | NOVARTIS AG (CH) | 2014-02-04 | — | — | US | disclosed |
| US-8557334-B2 | Silicone hydrogel lens with a covalently attached coating | NOVARTIS AG (CH) | 2013-10-15 | — | — | US | disclosed |
| US-8431624-B2 | Prepolymers suitable for making ultra-violet absorbing contact lenses | NOVARTIS AG (CH) | 2013-04-30 | — | — | US | disclosed |
| EP-2510052-A1 | A SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING | Novartis AG (CH) | 2012-10-17 | — | — | EP | disclosed |
| EP-2432821-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | Novartis AG (CH) | 2012-03-28 | — | — | EP | disclosed |
| EP-2374031-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | Novartis AG (CH) | 2011-10-12 | — | — | EP | disclosed |
| WO-2011071791-A1 | A SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING | NOVARTIS AG (CH) | 2011-06-16 | — | — | WO | disclosed |
| US-20110134387-A1 | SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING | ALCON INC. (CH) | 2011-06-09 | — | — | US | disclosed |
| WO-2011034801-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | NOVARTIS AG (CH) | 2011-03-24 | — | — | WO | disclosed |
| US-20110063567-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | ALCON INC. (CH) | 2011-03-17 | — | — | US | disclosed |
| WO-2010135481-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2010-11-25 | — | — | WO | disclosed |
| US-20100298446-A1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | ALCON INC. (CH) | 2010-11-25 | — | — | US | disclosed |
| US-20100258961-A1 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2010-10-14 | — | — | US | disclosed |
| WO-2010071691-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2010-06-24 | — | — | WO | disclosed |