SCHEMBL8615409

C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	SRD5A2	P31213	20/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8612171	1.00	SRD5A2 (1.00)	SRD5A2
SCHEMBL8072096	0.91	SRD5A2 (0.84)	SRD5A2
SCHEMBL8072095	0.91	SRD5A2 (0.84)	SRD5A2
SCHEMBL8611644	0.89	SRD5A2 (1.00)	SRD5A2
SCHEMBL8532138	0.89	SRD5A2 (1.00)	SRD5A2
SCHEMBL8378956	0.85	SRD5A2 (1.00)	SRD5A2
SCHEMBL8612779	0.85	SRD5A2 (1.00)	SRD5A2
SCHEMBL8612621	0.85	SRD5A2 (1.00)	SRD5A2
SCHEMBL8612777	0.85	SRD5A2 (1.00)	SRD5A2
SCHEMBL12606608	0.84	SRD5A2 (0.80)	SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0641356-B1	INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE	GLAXO WELLCOME INC (US)	1998-04-22	—	—	EP	claimed