SCHEMBL8615410

SCHEMBL8615410

CON=C(C(=O)OC)c1ccccc1Br

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.50
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
HTT P42858 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7040691 0.81 HIF1A (0.51) HIF1ANPC1RAB9AKMT2AMEN1
SCHEMBL29883529 0.81 HIF1A (0.51) HIF1ANPC1RAB9AKMT2AMEN1
SCHEMBL7119395 0.81 LMNA (0.55) HIF1ANPC1SMN1; SMN2KDM4EALDH1A1
SCHEMBL29445316 0.81 HIF1A (0.51) HIF1ANPC1RAB9AKMT2AMEN1
SCHEMBL6155893 0.81 HIF1A (0.51) HIF1ANPC1RAB9AKMT2AMEN1
SCHEMBL8617535 0.81 HIF1A (0.52) HIF1AKMT2AHTTKDM4EALDH1A1
SCHEMBL6705433 0.81 LMNA (0.55) HIF1ANPC1SMN1; SMN2KDM4EALDH1A1
SCHEMBL6705432 0.81 LMNA (0.55) HIF1ANPC1SMN1; SMN2KDM4EALDH1A1
SCHEMBL29810082 0.81 HIF1A (0.51) HIF1ANPC1RAB9AKMT2AMEN1
SCHEMBL3747106 0.81 HIF1A (0.51) HIF1ANPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5719171-A INSECTICIDES; MITICIDES; NEMATOCIDES; FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-02-17 US disclosed
US-5594020-A FUNGICIDE BASF AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
EP-0621277-A2 Diarylderivatives and their use for the protection of plants BASF Aktiengesellschaft (DE) 1994-10-26 EP disclosed