Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.60 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.60 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938852 | 0.79 | CYP24A1 (0.73) | CYP24A1CYP27A1CYP26A1CYP19A1ACHE | |
| SCHEMBL7245357 | 0.78 | CYP24A1 (0.80) | CYP24A1CYP27A1CYP26A1CYP19A1ACHE | |
| SCHEMBL630276 | 0.78 | CYP24A1 (0.70) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL14159089 | 0.76 | CYP24A1 (0.69) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL14165623 | 0.76 | CYP24A1 (0.66) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL4621871 | 0.76 | CYP24A1 (0.68) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL8012038 | 0.75 | METAP1 (0.78) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL7590283 | 0.75 | METAP1 (0.78) | CYP24A1CYP27A1CYP26A1CYP19A1METAP1 | |
| SCHEMBL8159828 | 0.75 | CYP26A1 (0.78) | CYP24A1CYP27A1CYP26A1CYP19A1ACHE | |
| SCHEMBL6827615 | 0.75 | CYP19A1 (1.00) | CYP24A1CYP27A1CYP26A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |