⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170823 | 0.73 | — | — | |
| SCHEMBL17640450 | 0.69 | — | — | |
| SCHEMBL14488458 | 0.69 | — | — | |
| SCHEMBL9158543 | 0.69 | — | — | |
| SCHEMBL18601354 | 0.64 | — | — | |
| SCHEMBL17163894 | 0.64 | — | — | |
| SCHEMBL560542 | 0.64 | — | — | |
| SCHEMBL1629124 | 0.62 | TSHR (0.35) | — | |
| SCHEMBL7949200 | 0.62 | — | — | |
| SCHEMBL25383610 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638548-B1 | Urea-subsituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them | HOECHST AG (DE) | 1998-04-22 | — | — | EP | disclosed |
| EP-0638548-A1 | Urea-subsituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-15 | — | — | EP | disclosed |