SCHEMBL8616351

SCHEMBL8616351

CC1(COCC2(C)CC=C([N+](=O)[O-])O2)CC=C([N+](=O)[O-])O1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11744646 0.71 MALT1 (0.31)
SCHEMBL9147377 0.68 AKR1B1 (0.32)
SCHEMBL29098139 0.63
SCHEMBL8768629 0.59 CYP1A2 (0.33) CYP1A2
SCHEMBL16344638 0.55
SCHEMBL6346351 0.53
SCHEMBL8313566 0.53 CYP1A2 (0.76) CYP1A2CYP2C9CYP2C19
SCHEMBL28950408 0.52 KCNA4 (0.43) CYP1A2CYP2C9CYP2C19
SCHEMBL2036083 0.51
Methoxymethane SCHEMBL27637909 0.49 HSD17B10 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811458-A USEFUL FOR PREVENTION 5-LIPOXYGENASE ACTIVITY IN LEUKAEMIA CELLS IN RODENTS AND IN HUMAN LEUKOCYTES REICHLING JURGEN (DE) 1998-09-22 US disclosed