SCHEMBL8616405

SCHEMBL8616405

CCO/N=C1/CCS(=O)(=O)c2ccc(C(=O)c3cnn(CC)c3O)c(C)c21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615782 1.00 POLB (0.34) POLBRAB9ASMN1; SMN2LMNA
SCHEMBL8550281 0.92 POLB (0.30) POLB
SCHEMBL8550283 0.92 POLB (0.30) POLB
SCHEMBL8545958 0.92 POLB (0.31) POLB
SCHEMBL8545954 0.92 POLB (0.31) POLB
SCHEMBL8460276 0.92 POLB (0.32) POLBRAB9ASMN1; SMN2LMNA
SCHEMBL8460273 0.92 POLB (0.32) POLBRAB9ASMN1; SMN2LMNA
SCHEMBL8870505 0.85 SPR (0.34)
SCHEMBL8870502 0.85 SPR (0.34)
SCHEMBL9038689 0.84 POLB (0.30) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506194-A CARBONYLTHIOCHROMAN HERBICIDES; PHYTOTOXICITY IDEMITSU KOSAN CO., LTD. (JP) 1996-04-09 US claimed
US-5849926-A Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 1998-12-15 US disclosed
US-5591868-A HERBICIDE INTERMEDIATES IDEMITSU KOSAN CO., LTD. (JP) 1997-01-07 US disclosed
EP-0728756-A1 PYRAZOLE DERIVATIVES AND HERBICIDE CONTAINING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-08-28 EP disclosed