Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616609 | 1.00 | RECQL (0.50) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL8618356 | 0.82 | HPGD (0.55) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL15918769 | 0.81 | HPGD (0.54) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL14823741 | 0.81 | HPGD (0.54) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL13599001 | 0.79 | HPGD (0.60) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL4465000 | 0.79 | RECQL (0.55) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL8065517 | 0.75 | HPGD (0.56) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL28660196 | 0.75 | RECQL (0.50) | RECQLHPGDGPR119PTPN2PTPN1 | |
| SCHEMBL7446544 | 0.75 | FAAH (0.43) | RECQLHPGDGPR119USP2SMN1; SMN2 | |
| SCHEMBL2015039 | 0.74 | HPGD (0.66) | RECQLHPGDGPR119PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786373-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-07-28 | — | — | US | disclosed |