Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620061 | 0.94 | MAPT (0.36) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8623629 | 0.89 | CA12 (0.36) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8619766 | 0.88 | MAPT (0.39) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8621400 | 0.86 | MAPT (0.43) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8616761 | 0.84 | CA12 (0.50) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8623637 | 0.83 | MAPT (0.40) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8620840 | 0.82 | MAPT (0.39) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8618708 | 0.81 | MAPT (0.39) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL8619789 | 0.81 | CDK2 (0.35) | ALDH1A1KDM4EKMT2AMEN1CA12 | |
| SCHEMBL8617973 | 0.81 | MAPT (0.38) | MAPTALDH1A1HPGDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |