Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616765 | 0.89 | MAPT (0.37) | CA12CA1CA2CA9DOT1L | |
| SCHEMBL8619789 | 0.89 | CDK2 (0.35) | CA12CA1CA2CA9CDK2 | |
| SCHEMBL8623647 | 0.88 | CDK2 (0.34) | CA12CA1CA2CA9CDK2 | |
| SCHEMBL8620061 | 0.87 | MAPT (0.36) | CA12CA1CA2CA9DOT1L | |
| SCHEMBL8623623 | 0.83 | CA12 (0.51) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8621400 | 0.83 | MAPT (0.43) | MAPTALDH1A1NPSR1KDM4ECYP1A2 | |
| SCHEMBL8619769 | 0.82 | CDK2 (0.36) | CA12CA1CA2CA9CDK2 | |
| SCHEMBL8617973 | 0.81 | MAPT (0.38) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL8617977 | 0.81 | CDK2 (0.34) | CA12CA1CA2CA9CDK2 | |
| SCHEMBL9036361 | 0.77 | CA12 (0.45) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |