Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490546 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL10841098 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9812996 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL14776761 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL16209744 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL2144618 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL10418032 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL11136138 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9062821 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL11134007 | 1.00 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435242-B2 | Compositions, devices, and methods for improving a surface property of a substrate | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-10-07 | — | — | US | claimed |
| US-20250163297-A1 | COMPOSITIONS, DEVICES, AND METHODS FOR IMPROVING A SURFACE PROPERTY OF A SUBSTRATE | AICP III LP | 2025-05-22 | — | — | US | claimed |
| US-20210171798-A1 | COMPOSITIONS, DEVICES, AND METHODS FOR IMPROVING A SURFACE PROPERTY OF A SUBSTRATE | AICP III LP | 2021-06-10 | — | — | US | claimed |
| EP-3794080-A2 | COMPOSITIONS, DEVICES, AND METHODS FOR IMPROVING A SURFACE PROPERTY OF A SUBSTRATE | The University of North Carolina at Chapel Hill (US) | 2021-03-24 | — | — | EP | claimed |
| CN-112154190-A | Composition, device and method for improving surface properties of a substrate | 北卡罗来纳-查佩尔山大学 | 2020-12-29 | — | — | CN | claimed |
| WO-2020068174-A2 | COMPOSITIONS, DEVICES, AND METHODS FOR IMPROVING A SURFACE PROPERTY OF A SUBSTRATE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2020-04-02 | — | — | WO | claimed |
| EP-2994474-B1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-12-20 | — | — | EP | claimed |
| US-9371339-B2 | Saturated and unsaturated silahydrocarbons via iron and cobalt pyridine diimine catalyzed olefin silylation | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-06-21 | — | — | US | claimed |
| EP-2994474-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | Momentive Performance Materials Inc. (US) | 2016-03-16 | — | — | EP | claimed |
| US-20140330036-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | PRINCETON UNIVERSITY (US) | 2014-11-06 | — | — | US | claimed |
| US-4973724-A | FUNCTIONAL FLUIDS | ETHYL CORPORATION (US) | 1990-11-27 | — | — | US | claimed |
| US-12435242-B2 | Compositions, devices, and methods for improving a surface property of a substrate | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250163297-A1 | COMPOSITIONS, DEVICES, AND METHODS FOR IMPROVING A SURFACE PROPERTY OF A SUBSTRATE | AICP III LP | 2025-05-22 | — | — | US | disclosed |
| US-12234377-B2 | Compositions, devices, and methods for improving a surface property of a substrate | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-02-25 | — | — | US | disclosed |
| EP-3794080-B1 | COMPOSITIONS, DEVICES, AND METHODS FOR IMPROVING A SURFACE PROPERTY OF A SUBSTRATE | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2024-04-10 | — | — | EP | disclosed |
| US-4650891-A | HALOSILANE AND GRIGNARD REAGENT, CYANIDE CATALYST | MONSANTO COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| US-4595777-A | Reacting alkylchlorosilane with trialkylaluminum compound | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1986-06-17 | — | — | US | disclosed |
| US-4578497-A | Tetraalkylsilane synthetic fluids | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| US-4572791-A | REACTING ALPHA-OLEFIN WITH DI-OR TRIALKYLSILANE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1986-02-25 | — | — | US | disclosed |
| US-4367343-A | Synthesis of tetraalkylsilanes | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330036-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | YAP1, LATS1, SIK1 | TSHR 4013/4885THRB 4513/4885CES2 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.