Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500714 | 0.82 | ELANE (0.58) | ELANECTRB1MEN1ALDH1A1KMT2A | |
| SCHEMBL8617012 | 0.79 | CTRB1 (0.59) | ELANECTRB1POLBMEN1ALDH1A1 | |
| SCHEMBL6499915 | 0.75 | ELANE (0.62) | ELANECTRB1 | |
| SCHEMBL27493723 | 0.75 | ELANE (0.62) | ELANECTRB1 | |
| SCHEMBL8700258 | 0.72 | ELANE (0.82) | ELANE | |
| SCHEMBL8702543 | 0.72 | ELANE (0.82) | ELANE | |
| SCHEMBL6499604 | 0.71 | CTRB1 (0.56) | ELANECTRB1MEN1ALDH1A1KMT2A | |
| SCHEMBL9693870 | 0.71 | ELANE (0.46) | ELANE | |
| SCHEMBL8699698 | 0.71 | ELANE (0.59) | ELANECTRB1 | |
| SCHEMBL6496779 | 0.71 | CTRB1 (0.56) | ELANECTRB1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | claimed |