SCHEMBL8617016

SCHEMBL8617016

CCC(C)(C)c1ccc(OC(=O)c2cccc(C(=O)O)c2-c2ccc(C(C)(C)CC)cc2C(C)(C)CC)c(C(C)(C)CC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
NPSR1 Q6W5P4 5/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 4/20 0.40
HTT P42858 3/20 0.40
UBE2N P61088 2/20 0.40
MITF O75030 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
CYP2C9 P11712 2/20 0.39
POLB P06746 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 2/20 0.37
CASP3 P42574 1/20 0.37
ATM Q13315 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9316818 0.86 NPSR1 (0.51) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL2449720 0.84 NPSR1 (0.55) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL1667250 0.78 MAPK1 (0.54) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL5030934 0.76 NPSR1 (0.52) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL2071016 0.76 MAPK1 (0.43) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL1953482 0.74 MAPK1 (0.62) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL3861061 0.74 MAPK1 (0.41) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL1636868 0.73 MAPK1 (0.60) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL8145475 0.72 MAPK1 (0.59) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL28378699 0.72 MAPK1 (0.59) MAPK1SMN1; SMN2NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0464612-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1998-05-13 EP disclosed
US-5547824-A CONTAINING SILVER HALIDE GRAINS HAVING LOWER SILVER IODIDE CONTENT ON SURFACES, COMPOUND CAPABLE OF RELEASING PHOTOGRAPHICALLY USEFUL GROUP THROUGH TIMING GROUP FUJI PHOTO FILM CO., LTD. (JP) 1996-08-20 US disclosed
EP-0501468-B1 Silver halide color photographic photosensitive materials FUJI PHOTO FILM CO LTD (JP) 1996-05-01 EP disclosed
US-5242787-A A support with a silver halide emulsion layer, a protective layer, a filter layer or an intermediate layer FUJI PHOTO FILM CO., LTD. (JP) 1993-09-07 US disclosed
US-5071735-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL CONTAINING A COMPOUND RELEASING A DIR COMMAND UPON REACTION WITH AN OXIDIZED DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1991-12-10 US disclosed
EP-0423742-A2 Silver halide color reversal photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-24 EP disclosed
EP-0316955-A2 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-05-24 EP disclosed