Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338709 | 0.70 | CYP19A1 (0.48) | HSD17B10CYP19A1MMP13GAARAB9A | |
| SCHEMBL7338035 | 0.70 | CYP19A1 (0.48) | HSD17B10CYP19A1MMP13GAARAB9A | |
| SCHEMBL27496396 | 0.68 | MMP12 (0.51) | CYP19A1MMP13MMP12RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7204871 | 0.65 | ERAP2 (0.51) | MMP13MMP12RAB9ASMN1; SMN2ANPEP | |
| Hydrochloric Acid SCHEMBL27556867 | 0.65 | ERAP2 (0.51) | MMP13MMP12RAB9ASMN1; SMN2ANPEP | |
| SCHEMBL30222646 | 0.65 | TSHR (0.38) | KDM4EL3MBTL1 | |
| SCHEMBL2353606 | 0.64 | GRM8 (0.51) | HSD17B10MMP13MMP12ANPEPERAP2 | |
| SCHEMBL1129871 | 0.64 | MMP12 (0.47) | MMP13MMP12RAB9ASMN1; SMN2ANPEP | |
| SCHEMBL1457765 | 0.64 | GRM8 (0.51) | HSD17B10MMP13MMP12ANPEPERAP2 | |
| SCHEMBL2353607 | 0.64 | GRM8 (0.51) | HSD17B10MMP13MMP12ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |