Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617090 | 1.00 | KMT2A (0.50) | KMT2ACYP19A1MAOBCHRM1CYP3A4 | |
| SCHEMBL9492980 | 0.86 | KMT2A (0.55) | KMT2ACHRM1 | |
| SCHEMBL7759295 | 0.84 | KMT2A (0.53) | KMT2ACHRM1 | |
| Oxalic Acid SCHEMBL9495879 | 0.81 | KMT2A (0.49) | KMT2ACHRM1 | |
| SCHEMBL8647579 | 0.79 | KMT2A (0.60) | KMT2ACHRM1 | |
| SCHEMBL8649491 | 0.79 | KMT2A (0.60) | KMT2ACHRM1 | |
| SCHEMBL8647576 | 0.79 | KMT2A (0.60) | KMT2ACHRM1 | |
| SCHEMBL9842900 | 0.78 | KMT2A (0.55) | KMT2ACHRM1 | |
| Hydrochloric Acid SCHEMBL8988266 | 0.76 | KMT2A (0.56) | KMT2ACHRM1 | |
| SCHEMBL8646167 | 0.75 | KMT2A (0.58) | KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596057-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | claimed |
| EP-0674636-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | claimed |
| WO-1994014804-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | claimed |
| EP-0596057-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-05-11 | — | — | EP | claimed |
| WO-1993021183-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | claimed |
| EP-0596057-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| EP-0674636-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-05-20 | — | — | EP | disclosed |
| EP-0674636-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014804-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |