Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9492479 | 0.94 | KMT2A (0.49) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9492980 | 0.91 | KMT2A (0.55) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL8988266 | 0.88 | KMT2A (0.56) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL9495879 | 0.85 | KMT2A (0.49) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL7759295 | 0.81 | KMT2A (0.53) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8617088 | 0.78 | KMT2A (0.50) | KMT2ACHRM1 | |
| SCHEMBL8617090 | 0.78 | KMT2A (0.50) | KMT2ACHRM1 | |
| SCHEMBL9491820 | 0.75 | MAP3K14 (0.47) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9492485 | 0.75 | KDM4E (0.38) | KMT2A | |
| SCHEMBL4689035 | 0.74 | KMT2A (0.57) | KMT2ACHRM1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412797-A2 | The therapeutic use of substituted benzenes, formulations thereof and novel substituted benzenes | MERCK SHARP & DOHME LTD. (GB) | 1991-02-13 | — | — | EP | claimed |
| EP-0412797-A2 | The therapeutic use of substituted benzenes, formulations thereof and novel substituted benzenes | MERCK SHARP & DOHME LTD. (GB) | 1991-02-13 | — | — | EP | disclosed |