Lithium

Lithium

SCHEMBL8617111

CCCC(C)COCC(C)CCC.[Li]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.35
EPHX2 P34913 1/20 0.32
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679319 0.97 TSHR (0.48) TSHRHSD17B10EPHX2CA12CA1
SCHEMBL19643118 0.97 TSHR (0.48) TSHRHSD17B10EPHX2CA12CA1
Calcium SCHEMBL10786902 0.94 TSHR (0.46) TSHRHSD17B10EPHX2CA12CA1
SCHEMBL10632086 0.94 TSHR (0.46) TSHRHSD17B10EPHX2CA12CA1
Potassium SCHEMBL10629925 0.94 TSHR (0.46) TSHRHSD17B10EPHX2CA12CA1
Barium SCHEMBL10787198 0.94 TSHR (0.46) TSHRHSD17B10EPHX2CA12CA1
SCHEMBL10789496 0.94 TSHR (0.46) TSHRHSD17B10EPHX2CA12CA1
Magnesium SCHEMBL8460788 0.94 TSHR (0.46) TSHRHSD17B10EPHX2CA12CA1
SCHEMBL2843100 0.89 TSHR (0.42) TSHRHSD17B10EPHX2
SCHEMBL13896143 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525880-B1 Catalytic alkylation process FMC CORP (US) 1998-05-06 EP claimed
US-5332853-A Alkylating tetrachlorosilane or an alkylchlorosilane with an alkyllithium using ether, metal alkoxide, amine, or metal amide as catalyst FMC CORPORATION (US) 1994-07-26 US claimed
EP-0525880-A1 Catalytic alkylation process FMC CORPORATION (US) 1993-02-03 EP claimed
US-4748283-A POLYMERIZATION CATALYSTS LITHIUM CORPORATION OF AMERICA (US) 1988-05-31 US claimed
US-4634786-A INTERMEDIATES FOR ZIEGLER CATALYSTS LITHIUM CORPORATION OF AMERICA (US) 1987-01-06 US claimed
EP-0162908-A4 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS. LITHIUM CORP (US) 1986-04-15 EP claimed
EP-0162908-A1 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS LITHIUM CORPORATION OF AMERICA (US) 1985-12-04 EP claimed
WO-1985002176-A1 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS LITHIUM CORPORATION OF AMERICA (US) 1985-05-23 WO claimed
EP-0525880-B1 Catalytic alkylation process FMC CORP (US) 1998-05-06 EP disclosed
US-5332853-A Alkylating tetrachlorosilane or an alkylchlorosilane with an alkyllithium using ether, metal alkoxide, amine, or metal amide as catalyst FMC CORPORATION (US) 1994-07-26 US disclosed
EP-0525880-A1 Catalytic alkylation process FMC CORPORATION (US) 1993-02-03 EP disclosed
US-4748283-A POLYMERIZATION CATALYSTS LITHIUM CORPORATION OF AMERICA (US) 1988-05-31 US disclosed
US-4634786-A INTERMEDIATES FOR ZIEGLER CATALYSTS LITHIUM CORPORATION OF AMERICA (US) 1987-01-06 US disclosed
EP-0162908-A4 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS. LITHIUM CORP (US) 1986-04-15 EP disclosed
EP-0162908-A1 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS LITHIUM CORPORATION OF AMERICA (US) 1985-12-04 EP disclosed
WO-1985002176-A1 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS LITHIUM CORPORATION OF AMERICA (US) 1985-05-23 WO disclosed