Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619188 | 0.94 | HRH3 (0.38) | ITGB3ITGA2BHRH3CYP19A1KDM4D | |
| SCHEMBL8621921 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BHRH3 | |
| SCHEMBL7371673 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BHRH3L3MBTL1TDP1 | |
| SCHEMBL8616963 | 0.75 | HRH3 (0.47) | HRH3CYP19A1L3MBTL1TDP1CYP1A2 | |
| SCHEMBL7337926 | 0.75 | KDM4D (0.39) | HRH3CYP19A1KDM4DL3MBTL1GPR119 | |
| SCHEMBL8624634 | 0.73 | HRH3 (0.44) | HRH3L3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL2565333 | 0.72 | ACE (0.49) | ITGB3ITGA2BL3MBTL1 | |
| SCHEMBL7342690 | 0.71 | ITGB3 (0.55) | ITGB3ITGA2BHRH3L3MBTL1TDP1 | |
| SCHEMBL7342693 | 0.71 | ITGB3 (0.79) | ITGB3ITGA2BHRH3 | |
| SCHEMBL7311668 | 0.70 | DDB1 (0.40) | L3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |