Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617317 | 1.00 | HIF1A (0.66) | HIF1AMCL1MRGPRX4MAOBMAPT | |
| SCHEMBL8618337 | 0.90 | HIF1A (0.67) | HIF1AMCL1MRGPRX4MAOBMAPT | |
| SCHEMBL8618334 | 0.90 | HIF1A (0.67) | HIF1AMCL1MRGPRX4MAOBMAPT | |
| SCHEMBL6460031 | 0.90 | HIF1A (0.67) | HIF1AMCL1MRGPRX4MAOBMAPT | |
| SCHEMBL8617460 | 0.90 | HIF1A (0.54) | HIF1AMCL1MRGPRX4MAOBL3MBTL1 | |
| SCHEMBL6460025 | 0.90 | HIF1A (0.67) | HIF1AMCL1MRGPRX4MAOBMAPT | |
| SCHEMBL8371507 | 0.90 | HIF1A (0.67) | HIF1AMCL1MRGPRX4MAOBMAPT | |
| SCHEMBL8617459 | 0.90 | HIF1A (0.54) | HIF1AMCL1MRGPRX4MAOBL3MBTL1 | |
| SCHEMBL8396210 | 0.86 | HIF1A (0.65) | HIF1AMCL1MRGPRX4MAOBKDM4E | |
| SCHEMBL8396217 | 0.86 | HIF1A (0.65) | HIF1AMCL1MRGPRX4MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |