Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.45 |
| ▸ | FNTB | P49356 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617640 | 1.00 | FNTA (0.45) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL7703375 | 1.00 | FNTA (0.45) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL7703378 | 1.00 | FNTA (0.45) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL7706112 | 0.91 | FNTA (0.46) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL7703276 | 0.91 | FNTA (0.46) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL7703271 | 0.91 | FNTA (0.46) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL8206537 | 0.91 | FNTA (0.46) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL7706109 | 0.91 | FNTA (0.46) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL7703293 | 0.88 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7703301 | 0.88 | FNTA (0.52) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |