Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 12/20 | 0.46 |
| ▸ | FNTB | P49356 | 12/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706112 | 1.00 | FNTA (0.46) | FNTAFNTBAGTR2PGGT1BUSP2 | |
| SCHEMBL7703271 | 1.00 | FNTA (0.46) | FNTAFNTBAGTR2PGGT1BUSP2 | |
| SCHEMBL7703276 | 1.00 | FNTA (0.46) | FNTAFNTBAGTR2PGGT1BUSP2 | |
| SCHEMBL7706109 | 1.00 | FNTA (0.46) | FNTAFNTBAGTR2PGGT1BUSP2 | |
| SCHEMBL7703300 | 0.93 | AGTR2 (0.45) | FNTAFNTBAGTR2PGGT1BCYP3A4 | |
| SCHEMBL7709015 | 0.93 | RAB9A (0.40) | FNTAFNTBAGTR2RAB9ACYP3A4 | |
| SCHEMBL7703291 | 0.93 | AGTR2 (0.45) | FNTAFNTBAGTR2PGGT1BCYP3A4 | |
| SCHEMBL7709010 | 0.93 | RAB9A (0.40) | FNTAFNTBAGTR2RAB9ACYP3A4 | |
| SCHEMBL7703353 | 0.92 | FNTA (0.48) | FNTAFNTBAGTR2PGGT1BUSP2 | |
| SCHEMBL7703349 | 0.92 | FNTA (0.48) | FNTAFNTBAGTR2PGGT1BUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | claimed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | claimed |