Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.37 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617661 | 1.00 | TSHR (0.41) | TSHRSMN1; SMN2MEN1KMT2ACASP1 | |
| SCHEMBL8463768 | 0.83 | HIF1A (0.35) | TSHRSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL8463766 | 0.83 | HIF1A (0.35) | TSHRSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL8435839 | 0.80 | TSHR (0.47) | TSHRSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL8435835 | 0.80 | TSHR (0.47) | TSHRSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL27478929 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL8460720 | 0.76 | MAPT (0.48) | TSHRSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL7773929 | 0.76 | HIF1A (0.47) | TSHRSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL8613981 | 0.76 | HIF1A (0.53) | TSHRSMN1; SMN2MEN1KMT2AHIF1A | |
| SCHEMBL8613983 | 0.76 | HIF1A (0.53) | TSHRSMN1; SMN2MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838452-A1 | PROCESS FOR PRODUCING N-METHYL-METHOXYIMINOACETAMIDE DERIVATIVES AND INTERMEDIATES THEREOF | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |