SCHEMBL8617813

SCHEMBL8617813

CO[Si](OC)(OC(C)C)C1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618201 0.98 CYP19A1 (0.30)
SCHEMBL28520399 0.95
SCHEMBL27959542 0.93 CYP19A1 (0.30)
SCHEMBL107614 0.88 CYP19A1 (0.30)
SCHEMBL105713 0.86 CYP19A1 (0.33)
SCHEMBL104826 0.86 CYP19A1 (0.33)
SCHEMBL103759 0.83
SCHEMBL8617415 0.81 KDM4E (0.32)
SCHEMBL80385 0.80
SCHEMBL10012485 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113785085-A Silicon oxide film, material for gas barrier film, and method for producing silicon oxide film 东曹株式会社 2021-12-10 CN disclosed
CN-108129591-B External electron donor composition, olefin polymerization catalyst system and application of external electron donor composition and olefin polymerization catalyst system 杨翠 2021-05-28 CN disclosed
CN-109790238-A Non-phthalate donors for polyolefin catalysts 格雷斯公司 2019-05-21 CN disclosed
EP-3240814-A1 CATALYST SYSTEMS, OLEFIN POLYMERIZATION CATALYST COMPONENTS COMPRISING AT LEAST AN INTERNAL ELECTRON DONOR COMPOUND, AND METHODS OF MAKING AND USING THE SAME W.R. GRACE & CO.-CONN. (US) 2017-11-08 EP disclosed
WO-2016109787-A1 CATALYST SYSTEMS, OLEFIN POLYMERIZATION CATALYST COMPONENTS COMPRISING AT LEAST AN INTERNAL ELECTRON DONOR COMPOUND, AND METHODS OF MAKING AND USING THE SAME BASF CORPORATION (US) 2016-07-07 WO disclosed
EP-0735056-B1 Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same TONEN CORP (JP) 1998-06-10 EP disclosed
US-5747595-A TRIALKOXYALKYLSILANE TONEN CORPORATION (JP) 1998-05-05 US disclosed
EP-0735056-A1 Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same Tonen Corporation (JP) 1996-10-02 EP disclosed
EP-0486116-B1 Silane compound and processes for the preparation thereof TONEN CORP (JP) 1995-06-28 EP disclosed
US-5142082-A SILANE COMPOUND AND PROCESSES FOR THE PREPARATION THEREOF TONEN CORPORATION (JP) 1992-08-25 US disclosed
US-5142082-A SILANE COMPOUND AND PROCESSES FOR THE PREPARATION THEREOF TONEN CORPORATION (JP) 1992-08-25 US disclosed
EP-0486116-A1 Silane compound and processes for the preparation thereof Tonen Corporation (JP) 1992-05-20 EP disclosed
EP-0486116-A1 Silane compound and processes for the preparation thereof Tonen Corporation (JP) 1992-05-20 EP disclosed