SCHEMBL8617860

SCHEMBL8617860

NCCOc1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.51
CCR5 P51681 3/20 0.51
CCR8 P51685 3/20 0.51
KDM4E B2RXH2 6/20 0.50
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
ALOX15 P16050 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
HSP90AA1 P07900 2/20 0.50
TP53 P04637 2/20 0.50
HTT P42858 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALPL P05186 1/20 0.50
ALPI P09923 1/20 0.50
ALPG P10696 1/20 0.50
MAPK1 P28482 1/20 0.50
TAAR1 Q96RJ0 1/20 0.48
CYP1A2 P05177 2/20 0.47
POLB P06746 1/20 0.47
METAP1 P53582 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17783303 0.89 CCR1 (0.47) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL13303083 0.86 CCR1 (0.55) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL12131380 0.83 CCR1 (0.51) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL13596182 0.83 CYP1A2 (0.55) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL7790789 0.82 CYP2D6 (0.67) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL30930809 0.82 CCR1 (0.50) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL9678486 0.82 CCR1 (0.50) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL17899680 0.82 CCR1 (0.50) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL19785968 0.80 CCR1 (0.45) CCR1CCR5CCR8KDM4ELMNA
Dipyridyl SCHEMBL16445111 0.80 KDM4E (0.74) CCR1CCR5CCR8KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180016401-A1 FUNCTIONALIZED SILOXANE MATERIALS MOMENTIVE PERFORMANCE MATERIALS INC. 2018-01-18 US disclosed
US-20170369715-A1 LUMINESCENT SILICONE COATINGS MOMENTIVE PERFORMANCE MATERIALS INC. 2017-12-28 US disclosed
EP-0576036-B1 Optical information recording element using AZO dyes EASTMAN KODAK CO (US) 1998-05-20 EP disclosed
EP-0576036-A2 Optical information recording element using AZO dyes EASTMAN KODAK COMPANY (US) 1993-12-29 EP disclosed
US-5272047-A Optical information recording medium using azo dyes EASTMAN KODAK COMPANY (US) 1993-12-21 US disclosed
EP-0187984-B1 POLYMERIC MORDANT CONTAINING NITROGEN-COORDINATING LIGAND FOR METALLIZABLE DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-11-09 EP disclosed
EP-0187984-A1 Polymeric mordant containing nitrogen-coordinating ligand for metallizable dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-23 EP disclosed
EP-0187340-A1 Photographic products employing novel nondiffusible metal complexes of AZO dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-16 EP disclosed
US-4599389-A COLOR PHOTOGRAPHY DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1986-07-08 US disclosed
US-4598030-A Photographic products employing novel nondiffusible metal complexes of azo dyes EASTMAN KODAK COMPANY (US) 1986-07-01 US disclosed
US-4581314-A FOR COLOR DIFFUSION TRANSFER PHOTOGRAPHY; RAPID DYE METALLIZATION EASTMAN KODAK COMPANY (US) 1986-04-08 US disclosed