Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.34 |
| ▸ | FBP1 | P09467 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622360 | 0.92 | SIRT2 (0.40) | SIRT2PARP1GRIN1GRIN2DGRIN3B | |
| SCHEMBL8618985 | 0.88 | SIRT2 (0.37) | SIRT2PARP1FBP1KDM4ELMNA | |
| SCHEMBL8617919 | 0.85 | SIRT2 (0.43) | SIRT2PARP1GRIN1GRIN2DGRIN3B | |
| SCHEMBL8622359 | 0.84 | SIRT2 (0.39) | SIRT2GRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8616707 | 0.82 | SIRT2 (0.38) | SIRT2PARP1FBP1KDM4ELMNA | |
| SCHEMBL8619552 | 0.81 | SIRT2 (0.41) | SIRT2PARP1GRIN1GRIN2DGRIN3B | |
| SCHEMBL9036978 | 0.81 | SIRT2 (0.32) | SIRT2PARP1 | |
| SCHEMBL8620025 | 0.78 | SIRT2 (0.39) | SIRT2PARP1FBP1KDM4EMAPT | |
| SCHEMBL8620799 | 0.78 | SIRT2 (0.37) | SIRT2GRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8618714 | 0.78 | GRIA1 (0.44) | SIRT2PARP1GRIN1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |