Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131804 | 0.87 | MAOB (0.60) | SRD5A2NR4A2MAOBNR4A1NR4A3 | |
| SCHEMBL26863 | 0.85 | MAOB (0.71) | SRD5A2NR4A2MAOBPTGESNR4A1 | |
| SCHEMBL29481015 | 0.85 | MAOB (0.71) | SRD5A2NR4A2MAOBPTGESNR4A1 | |
| SCHEMBL5119495 | 0.85 | SRD5A2 (0.59) | SRD5A2NR4A2MAOBPTGESNR4A1 | |
| SCHEMBL7480033 | 0.84 | SRD5A2 (0.66) | SRD5A2NR4A2MAOBPTGESNR4A1 | |
| Benzophenone SCHEMBL28215327 | 0.84 | MAOB (0.69) | SRD5A2NR4A2MAOBPTGESNR4A1 | |
| SCHEMBL14315506 | 0.83 | SRD5A2 (0.60) | SRD5A2NR4A2MAOBPTGESNR4A1 | |
| SCHEMBL4125549 | 0.82 | MAOB (0.58) | NR4A2MAOBNR4A1NR4A3SMN1; SMN2 | |
| SCHEMBL5377638 | 0.81 | SRD5A2 (0.58) | SRD5A2NR4A2MAOBPTGESNR4A1 | |
| SCHEMBL2686883 | 0.81 | PTGES (0.70) | SRD5A2NR4A2MAOBPTGESNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723458-A | 1,4-BENZOTHIAZEPINES | GLAXO WELLCOME INC. (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0683774-A1 | HYPOLIPIDAEMIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018184-A1 | HYPOLIPIDAEMIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-08-18 | — | — | WO | disclosed |