Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618298 | 1.00 | ALDH1A1 (0.47) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL22455043 | 1.00 | ALDH1A1 (0.47) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8618084 | 0.95 | DPP8 (0.47) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8618076 | 0.95 | DPP8 (0.47) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL20510130 | 0.94 | DPP8 (0.46) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL10441465 | 0.92 | IDO1 (0.53) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL4161005 | 0.92 | IDO1 (0.53) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL1840095 | 0.90 | ALDH1A1 (0.50) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL535584 | 0.90 | ALDH1A1 (0.50) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28986973 | 0.90 | IDO1 (0.52) | ALDH1A1IDO1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1187360-C | Phosphonic acid derivs, having carboxypeptidase B inhibitory activity | MEIJI SEIKA KAISHA (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1373766-A | Phosphonic acid derivatives having carboxypeptidase B inhibitory activity | MEIJI SEIKA KAISHA (JP) | 2002-10-09 | — | — | CN | disclosed |
| US-5710324-A | AMINE CONTAINING COMPOUNDS | MERRELL PHARMACEUTICALS INC. (US) | 1998-01-20 | — | — | US | disclosed |
| US-5318992-A | Administering for the treatment of hypotensive conditions and shock | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0446699-A1 | Inhibitors of nitric oxide biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-09-18 | — | — | EP | disclosed |