Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.45 |
| ▸ | PGR | P06401 | 16/20 | 0.41 |
| ▸ | AR | P10275 | 14/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407402 | 0.92 | NR3C1 (0.54) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8407284 | 0.89 | NR3C1 (0.41) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8407111 | 0.85 | NR3C1 (0.38) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL8407053 | 0.83 | NR3C1 (0.36) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL8408969 | 0.81 | NR3C1 (0.48) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8620050 | 0.80 | NR3C1 (0.47) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8407360 | 0.80 | NR3C1 (0.47) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8407253 | 0.80 | NR3C1 (0.49) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8408961 | 0.79 | NR3C1 (0.57) | NR3C1PGRARCYP2C8 | |
| SCHEMBL8622523 | 0.78 | NR3C1 (0.59) | NR3C1PGRARCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |