Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ACP1 | P24666 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616443 | 0.93 | ACP1 (0.41) | LMNASMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL8617530 | 0.90 | ACP1 (0.43) | LMNASMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL8617872 | 0.90 | ACP1 (0.42) | LMNASMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL8614870 | 0.89 | ACP1 (0.41) | LMNASMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL8617748 | 0.89 | ACP1 (0.52) | LMNASMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL8620930 | 0.87 | PDE10A (0.44) | SMN1; SMN2ACP1MEN1KMT2APDE10A | |
| SCHEMBL8620369 | 0.86 | MEN1 (0.43) | LMNASMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL8615054 | 0.86 | PDE10A (0.55) | LMNASMN1; SMN2ACP1MEN1KMT2A | |
| SCHEMBL8613181 | 0.84 | ACP1 (0.38) | SMN1; SMN2ACP1MEN1KMT2APDE10A | |
| SCHEMBL8614063 | 0.84 | PDE10A (0.46) | LMNASMN1; SMN2ACP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |