Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615851 | 0.92 | ACP1 (0.36) | ACP1MEN1KMT2AABCB1ABCC1 | |
| SCHEMBL8615156 | 0.90 | ACP1 (0.37) | ACP1MEN1KMT2AABCB1ABCC1 | |
| SCHEMBL8619253 | 0.89 | ACP1 (0.37) | ACP1MEN1KMT2AABCB1ABCC1 | |
| SCHEMBL8617284 | 0.88 | PDE10A (0.38) | ACP1MEN1KMT2APDE10ATSHR | |
| SCHEMBL8620892 | 0.85 | HTT (0.47) | ACP1MEN1KMT2AHTTGALR3 | |
| SCHEMBL8618733 | 0.84 | LMNA (0.45) | ACP1MEN1KMT2AHTTPDE10A | |
| SCHEMBL8616012 | 0.84 | PDE10A (0.40) | ACP1MEN1KMT2AABCB1ABCC1 | |
| SCHEMBL8616415 | 0.84 | ACP1 (0.42) | ACP1MEN1KMT2AABCB1ABCC1 | |
| SCHEMBL8613901 | 0.84 | ACP1 (0.51) | ACP1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL8616287 | 0.83 | PDE10A (0.49) | ACP1MEN1KMT2AABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |