SCHEMBL8618879

SCHEMBL8618879

Oc1ccc(CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.47
ESR2 Q92731 12/20 0.42
BLM P54132 1/20 0.38
ABAT P80404 1/20 0.37
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
SLC6A2 P23975 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTR3A P46098 1/20 0.34
BACE1 P56817 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618196 1.00 ESR1 (0.47) ESR1ESR2BLMABATCA2
SCHEMBL1241822 1.00 ESR1 (0.47) ESR1ESR2BLMABATCA2
SCHEMBL8614521 1.00 ESR1 (0.47) ESR1ESR2BLMABATCA2
SCHEMBL8617744 1.00 ESR1 (0.47) ESR1ESR2BLMABATCA2
SCHEMBL8617309 1.00 ESR1 (0.47) ESR1ESR2BLMABATCA2
SCHEMBL8613505 1.00 ESR1 (0.47) ESR1ESR2BLMABATCA2
SCHEMBL7156898 0.81 ESR1 (0.46) ESR1ESR2BLMCA2KDM4E
SCHEMBL25693125 0.80 IDO1 (0.37) CA2TAAR1
SCHEMBL19911654 0.76 ALDH1A1 (0.39) ALDH1A1
SCHEMBL9770633 0.76 ALDH1A1 (0.45) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed