SCHEMBL8618969

SCHEMBL8618969

Cl[Ni]Cl.c1ccc([PH](CCC[PH](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3158018 0.90 TRPA1 (0.31) TSHR
SCHEMBL106258 0.90 TSHR (0.39) TSHR
SCHEMBL5232942 0.87 TSHR (0.38) TSHR
Bromide SCHEMBL30490539 0.87 TSHR (0.38) TSHR
SCHEMBL838143 0.85 TSHR (0.39) TSHR
SCHEMBL12787151 0.82 TSHR (0.38) TSHR
SCHEMBL12787153 0.82 TSHR (0.38) TSHR
SCHEMBL837455 0.82 TSHR (0.38) TSHR
SCHEMBL12787155 0.82 TSHR (0.38) TSHR
SCHEMBL11897049 0.82 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5719303-A USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA EISAI CO., LTD. (JP) 1998-02-17 US disclosed