Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 13/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 12/20 | 1.00 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 1.00 |
| ▸ | PARP1 | P09874 | 6/20 | 0.78 |
| ▸ | GUSB | P08236 | 7/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.72 |
| ▸ | WNT3A | P56704 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885282 | 0.92 | TNKS (0.93) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL6124189 | 0.88 | TNKS (0.93) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL29592833 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL258433 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB | |
| Hydrochloric Acid SCHEMBL31529601 | 0.86 | TNKS (0.96) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL28135157 | 0.84 | TNKS (0.73) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL7765127 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL15775207 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL2006170 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL29764113 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241447-A | Method for synthesizing quinazolinone and derivative thereof through photocatalysis three-component serial reaction | 淮阴工学院 | 2025-01-03 | — | — | CN | disclosed |
| CN-116159594-B | Application of pyridinium small molecule as photocatalyst in alcohol and amine series reaction | 北京理工大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-115650924-B | Green synthesis method of quinazolinone | 山东华泰新材料技术研发有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-117964560-A | Method for constructing quinazolinone derivative through oxidization | 淮阴工学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-116159594-A | Application of pyridinium small molecule as photocatalyst in alcohol and amine series reaction | 北京理工大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-115650924-A | Green synthesis method of quinazolinone | 上海橡实化学有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-112645887-B | Preparation method of quinazolinone derivative | 淮阴工学院（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-112645887-A | Preparation method of quinazolinone derivative | 淮阴工学院 | 2021-04-13 | — | — | CN | disclosed |
| CN-104910079-A | Method for preparing 4(3H)-quinazolinone derivative through toluene and derivative oxidation one-pot process | UNIV TONGJI | 2015-09-16 | — | — | CN | disclosed |
| CN-103880761-B | The method of one pot process 4 (3H)-Quinazol derivative is eliminated by cyclization | TIANJIN UNIVERSITY (CN) | 2015-07-29 | — | — | CN | disclosed |
| CN-104557738-A | Green synthesis method of 4(3H)-quinazolinone | UNIV HUNAN | 2015-04-29 | — | — | CN | disclosed |
| CN-103880761-A | Method for synthesizing 4(3H)-quinazolinone derivative by using cyclization elimination one-pot method | UNIV TIANJIN | 2014-06-25 | — | — | CN | disclosed |
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |
| CN-101429165-B | Synthesis of quinazoline ketone compounds | UNIV WENZHOU | 2011-02-16 | — | — | CN | disclosed |
| CN-101429165-A | Synthesis of quinazoline ketone compounds | UNIV WENZHOU (CN) | 2009-05-13 | — | — | CN | disclosed |
| US-5849861-A | Polyquinazolines and methods for their preparation | HITACHI CHEMICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| US-5686560-A | TREATING A MONOMER WITH A BASE IN A DIPOLAR SOLVENT | HITACHI CHEMICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |