Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 13/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 12/20 | 1.00 |
| ▸ | PARP1 | P09874 | 6/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.81 |
| ▸ | GUSB | P08236 | 6/20 | 0.78 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.78 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.78 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | WNT3A | P56704 | 1/20 | 0.71 |
| ▸ | CASP3 | P42574 | 1/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.71 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592833 | 1.00 | TNKS (1.00) | TNKSTNKS2PARP1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL31529601 | 0.98 | TNKS (0.96) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL6124189 | 0.96 | TNKS (0.93) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL6885282 | 0.96 | TNKS (0.93) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL8620410 | 0.91 | TNKS (0.83) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL6695759 | 0.90 | TNKS2 (0.81) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL29831923 | 0.90 | HPGD (1.00) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL3460177 | 0.90 | HPGD (1.00) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL16768506 | 0.88 | TNKS (0.78) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL8618982 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027093-A | Siloxane ligand protected V6Nanocluster, synthesis method and catalytic application thereof | 山东交通学院 | 2024-05-14 | — | — | CN | claimed |
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | claimed |
| EP-3160960-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2017-05-03 | — | — | EP | claimed |
| WO-2015200352-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-30 | — | — | WO | claimed |
| EP-1761540-A1 | QUINAZOLINONES AS INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | ICOS CORPORATION (US) | 2007-03-14 | — | — | EP | claimed |
| WO-2005113556-A1 | QUINAZOLINONES AS INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | ICOS CORPORATION (US) | 2005-12-01 | — | — | WO | claimed |
| US-6479499-B1 | INHIBITORS OF TUBULIN POLYMERIZATION | NATIONAL SCIENCE COUNCIL (TW) | 2002-11-12 | — | — | US | claimed |
| CN-115650924-B | Green synthesis method of quinazolinone | 山东华泰新材料技术研发有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118027093-A | Siloxane ligand protected V6Nanocluster, synthesis method and catalytic application thereof | 山东交通学院 | 2024-05-14 | — | — | CN | disclosed |
| CN-117964560-A | Method for constructing quinazolinone derivative through oxidization | 淮阴工学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-117561063-A | Heterocyclic compounds and methods of use | 安进公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-111777564-B | Method for synthesizing quinazolinone compound by photocatalytic alcohol oxidation in aqueous phase | 许昌学院 | 2023-07-14 | — | — | CN | disclosed |
| CN-114591251-B | Chiral aminoquinazoline compound, and preparation method and application thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |
| EP-0013612-A2 | (Piperidinylalkyl)quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-07-23 | — | — | EP | disclosed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |
| US-3998951-A | Substituted 2-arylquinazolines as fungicides | FMC CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
| US-3932409-A | CYTOSTATIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
| US-3932409-A | CYTOSTATIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |