SCHEMBL8619002

SCHEMBL8619002

Cc1cc(O)c(C(=O)c2ccccc2)c(O)c1C(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
POLB P06746 1/20 0.49
ALDH1A1 P00352 5/20 0.46
BCL2 P10415 1/20 0.46
MCL1 Q07820 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
ATM Q13315 1/20 0.45
LMNA P02545 3/20 0.45
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.44
MEN1 O00255 2/20 0.44
USP2 O75604 1/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
CYP3A4 P08684 2/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30550350 0.86 ALDH1A1 (0.56) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL11484517 0.83 BCL2L1 (0.51) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL28618526 0.81 BCL2L1 (0.50) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL8965058 0.81 CYP3A4 (0.63) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL11482949 0.81 KMT2A (0.50) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL28515130 0.81 BCL2L1 (0.50) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL19509225 0.81 BCL2L1 (0.50) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL8399976 0.79 GAA (0.55) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1
SCHEMBL11491965 0.79 ALDH1A1 (0.52) BCL2L1L3MBTL1ALDH1A1GABRA1GABRB1
SCHEMBL29727844 0.79 ALDH1A1 (0.52) BCL2L1L3MBTL1SMN1; SMN2POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0668313-B1 Silylated agents useful for absorbing ultraviolet light GEN ELECTRIC (US) 1998-05-13 EP disclosed
EP-0668313-A1 Silylated agents useful for absorbing ultraviolet light GENERAL ELECTRIC COMPANY (US) 1995-08-23 EP disclosed
US-5391795-A Incorporated with silanetriol hardcoat over a polycarbonate substrate; wear and radiation resistance GENERAL ELECTRIC COMPANY (US) 1995-02-21 US disclosed