Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619275 | 1.00 | TNNC1 (0.51) | TNNC1ATMLMNAXBP1SMN1; SMN2 | |
| SCHEMBL14401828 | 0.92 | TNNC1 (0.43) | TNNC1ATMLMNAXBP1SMN1; SMN2 | |
| SCHEMBL7631405 | 0.88 | CYP2C19 (0.42) | TNNC1CYP2C19KDM4EALDH1A1HPGD | |
| SCHEMBL7631408 | 0.88 | CYP2C19 (0.42) | TNNC1CYP2C19KDM4EALDH1A1HPGD | |
| SCHEMBL6046924 | 0.88 | TNNC1 (0.55) | TNNC1KCNH2FAAHTRPV1ALDH1A1 | |
| SCHEMBL7122640 | 0.84 | CYP2C19 (0.44) | LMNASMN1; SMN2NPSR1GPR183CYP2C19 | |
| SCHEMBL7122638 | 0.84 | CYP2C19 (0.44) | LMNASMN1; SMN2NPSR1GPR183CYP2C19 | |
| SCHEMBL1001650 | 0.81 | TNNC1 (0.55) | TNNC1LMNANPSR1TRPV1CYP2C19 | |
| SCHEMBL1277033 | 0.81 | TNNC1 (0.55) | TNNC1LMNANPSR1TRPV1CYP2C19 | |
| SCHEMBL1140653 | 0.81 | TNNC1 (0.51) | TNNC1KCNH2FAAHTRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |