SCHEMBL8619703

SCHEMBL8619703

Cc1ccc(CNc2ccc(-c3ccncc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
MEN1 O00255 2/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 2/20 0.59
KDM4E B2RXH2 2/20 0.59
HPGD P15428 2/20 0.59
GAA P10253 2/20 0.59
POLB P06746 1/20 0.59
HSP90AA1 P07900 1/20 0.59
HSP90AB1 P08238 1/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
MAPK1 P28482 1/20 0.59
CASP1 P29466 1/20 0.59
BLM P54132 1/20 0.59
PLEC Q15149 1/20 0.59
HSD17B10 Q99714 1/20 0.59
HTT P42858 1/20 0.58
RAB9A P51151 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL171805 0.89 HTT (0.66) ALDH1A1L3MBTL1MEN1MAPTKMT2A
SCHEMBL19241983 0.85 KDM4E (0.56) ALDH1A1MAPTKDM4EGAAPOLB
SCHEMBL19241982 0.85 F2 (0.56) ALDH1A1MAPTKDM4EGAAHSD17B10
SCHEMBL2005375 0.83 MAPT (0.80) ALDH1A1L3MBTL1MEN1MAPTKMT2A
SCHEMBL10055032 0.83 MAPT (0.80) ALDH1A1L3MBTL1MEN1MAPTKMT2A
SCHEMBL11512045 0.82 HTT (0.79) ALDH1A1L3MBTL1MEN1MAPTKMT2A
SCHEMBL11935945 0.81 MAPT (0.61) ALDH1A1L3MBTL1MEN1MAPTKMT2A
SCHEMBL17448681 0.80 HTT (0.75) ALDH1A1L3MBTL1MEN1MAPTKMT2A
SCHEMBL19242049 0.79 KDM4E (0.61) ALDH1A1MAPTKDM4EGAAPOLB
SCHEMBL19242051 0.79 F2 (0.61) ALDH1A1MAPTKDM4EGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
EP-0665119-B1 Thermochromic colour-memory composition PILOT INK CO LTD (JP) 1997-12-03 EP disclosed
US-5558699-A COLOR IS RETAINED AFTER HEATING OR COOLING IS WITHDRAWN, REACTION MEDIUM IS ALKYL OR ALKYLARYL KETONE THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0665119-A1 Thermochromic colour-memory composition THE PILOT INK CO., LTD. (JP) 1995-08-02 EP disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
US-3985376-A Dye precursors for pressure-sensitive recording material BASF AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed