Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420448 | 0.84 | KMT2A (0.55) | KMT2APTPN5PARP10NR1H4ALDH1A1 | |
| SCHEMBL28302793 | 0.80 | MAPT (0.50) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL16579071 | 0.79 | KMT2A (0.53) | KMT2APTPN5PARP10NR1H4ALDH1A1 | |
| SCHEMBL28846044 | 0.78 | MAPT (0.41) | KMT2AALDH1A1KDM4ELMNAMAPK1 | |
| SCHEMBL27608748 | 0.77 | PDK1 (0.51) | KMT2APARP10ALDH1A1POLBLMNA | |
| SCHEMBL14175128 | 0.77 | SMN1; SMN2 (0.36) | KMT2ACYP3A4MEN1SMN1; SMN2 | |
| SCHEMBL30087591 | 0.76 | PARP10 (0.56) | KMT2APTPN5PARP10NR1H4ALDH1A1 | |
| SCHEMBL1819925 | 0.76 | CXCR2 (0.48) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3574727 | 0.76 | CXCR2 (0.48) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3582579 | 0.76 | CXCR2 (0.48) | KMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998057910-A2 | CYCLOOXYGENASE-I SELECTIVE INHIBITORS AND THE USE THEREOF AS ANALGESIC, ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1998-12-23 | — | — | WO | disclosed |