Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 2/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623033 | 0.82 | NCEH1 (0.57) | HSP90AA1CRHBPCRHR2TSHRNCEH1 | |
| SCHEMBL1305741 | 0.82 | MEN1 (0.54) | HSP90AA1CRHBPCRHR2MEN1ESR1 | |
| SCHEMBL7064923 | 0.80 | MEN1 (0.51) | HSP90AA1CRHBPCRHR2NCEH1MEN1 | |
| SCHEMBL8153401 | 0.80 | KMT2A (0.51) | HSP90AA1CRHBPCRHR2MEN1ESR1 | |
| SCHEMBL1073454 | 0.79 | MEN1 (0.68) | MEN1ESR1GAAKMT2AESR2 | |
| SCHEMBL6942534 | 0.78 | KMT2A (0.71) | MEN1ESR1GAAKMT2AESR2 | |
| SCHEMBL14075539 | 0.77 | MEN1 (0.49) | HSP90AA1CRHBPCRHR2MEN1ESR1 | |
| SCHEMBL29625716 | 0.77 | NCEH1 (0.64) | HSP90AA1CRHBPCRHR2TSHRNCEH1 | |
| SCHEMBL4594864 | 0.77 | NCEH1 (0.64) | HSP90AA1CRHBPCRHR2TSHRNCEH1 | |
| SCHEMBL6753875 | 0.76 | MEN1 (0.48) | HSP90AA1CRHBPCRHR2MEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |