SCHEMBL6942534

SCHEMBL6942534

Cc1ccc(S(=O)(=O)Oc2ccc(OS(=O)(=O)c3ccc(C)cc3)c3ccccc23)cc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.71
MEN1 O00255 7/20 0.71
GAA P10253 3/20 0.71
ESR1 P03372 2/20 0.71
ESR2 Q92731 2/20 0.71
LMNA P02545 3/20 0.55
MAPK1 P28482 1/20 0.55
KEAP1 Q14145 2/20 0.51
NFE2L2 Q16236 2/20 0.51
ALDH1A1 P00352 5/20 0.49
MAPT P10636 4/20 0.49
VDR P11473 1/20 0.47
GFER P55789 1/20 0.47
HTT P42858 1/20 0.46
HTR6 P50406 1/20 0.46
PKM P14618 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935953 0.93 KMT2A (0.64) KMT2AMEN1GAAESR1ESR2
SCHEMBL3811146 0.91 KMT2A (0.61) KMT2AMEN1GAAESR1ESR2
Hydrogen Sulfide SCHEMBL27642870 0.89 KMT2A (0.81) KMT2AMEN1GAAESR1ESR2
SCHEMBL4076148 0.89 KMT2A (0.59) KMT2AMEN1GAAESR1ESR2
SCHEMBL2066156 0.89 KMT2A (0.59) KMT2AMEN1GAAESR1ESR2
SCHEMBL13924690 0.89 KMT2A (0.59) KMT2AMEN1GAAESR1ESR2
SCHEMBL482651 0.88 KMT2A (0.62) KMT2AMEN1GAAESR1ESR2
SCHEMBL4081984 0.88 KMT2A (0.58) KMT2AMEN1GAAESR1ESR2
SCHEMBL3871600 0.88 KMT2A (0.58) KMT2AMEN1GAAESR1ESR2
SCHEMBL4076149 0.87 KMT2A (0.60) KMT2AMEN1GAAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
US-6365776-B1 FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-04-02 US disclosed
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TAKASAGO INTERNATIONAL CORPORATION 2002-03-21 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TYR, DDC, PNMT KMT2A 359/4885MEN1 1606/4885GAA 1735/4885
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 KMT2A 170/4885MEN1 2881/4885GAA 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.