Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682980 | 0.95 | HTT (0.77) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL446113 | 0.95 | HTT (0.77) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29839667 | 0.93 | HTT (0.81) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8434168 | 0.93 | HTT (0.81) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL9633469 | 0.93 | HTT (0.74) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL713317 | 0.87 | HTT (0.67) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3826756 | 0.85 | HTT (0.65) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1270519 | 0.85 | HTT (0.65) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1537710 | 0.85 | HTT (0.70) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL28411450 | 0.84 | CTNNB1 (0.66) | HTTKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840802-A | HEAT RESISTANCE AND IMPACT STRENGTH FOR THERMOPLASTIC RESINS | GENERAL ELECTRIC COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0537014-A2 | Dual graft stage and thermally stabilized polyorganisiloxane/polyvinyl-based graft copolymers and thermoplastic compositions containing the same | GENERAL ELECTRIC COMPANY (US) | 1993-04-14 | — | — | EP | disclosed |