Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619539 | 0.92 | HPGD (0.59) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8616688 | 0.91 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8613529 | 0.91 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8621032 | 0.91 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8621478 | 0.91 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8615172 | 0.91 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9036946 | 0.91 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8619200 | 0.89 | HPGD (0.57) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8616296 | 0.88 | HPGD (0.57) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8619397 | 0.88 | HPGD (0.57) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |