Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.32 |
| ▸ | IL1RN | P18510 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623203 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL8623465 | 0.72 | HPGD (0.49) | ANPEPIL1RNERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL19031573 | 0.71 | HPGD (0.48) | ANPEP | |
| SCHEMBL18365760 | 0.71 | PRKACA (0.34) | — | |
| SCHEMBL1270418 | 0.70 | NPC1 (0.52) | ANPEPIL1RNERAP2ERAP1 | |
| SCHEMBL1270022 | 0.70 | NPC1 (0.52) | ANPEPIL1RNERAP2ERAP1 | |
| SCHEMBL13904707 | 0.70 | NPC1 (0.52) | ANPEPIL1RNERAP2ERAP1 | |
| SCHEMBL1269652 | 0.70 | NPC1 (0.52) | ANPEPIL1RNERAP2ERAP1 | |
| SCHEMBL6099018 | 0.70 | NPC1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL25379502 | 0.69 | ANPEP (0.53) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789587-A | Heterocyclic-fused lactams promote release of growth hormone | MERCK & CO., INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5606054-A | Heterocyclic-fused lactams promote release of growth hormone | MERCK & CO., INC. (US) | 1997-02-25 | — | — | US | disclosed |