Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713932 | 1.00 | AHCY (0.54) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL13890093 | 1.00 | AHCY (0.54) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL8620317 | 1.00 | AHCY (0.54) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL13873163 | 1.00 | AHCY (0.54) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL8618543 | 0.90 | SLC29A1 (0.46) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL8623428 | 0.90 | SLC29A1 (0.46) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL8620282 | 0.90 | SLC29A1 (0.46) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL8618540 | 0.90 | SLC29A1 (0.46) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL8623422 | 0.90 | SLC29A1 (0.46) | AHCYNT5EADORA2AADORA3PDE4D | |
| SCHEMBL8923952 | 0.90 | NT5E (0.62) | AHCYNT5EADORA2AADORA3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314011-A2 | Purine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-05-03 | — | — | EP | claimed |
| US-5817799-A | 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0540686-B1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5336764-A | 2'-fluorofuranosyl derivatives and novel method of preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-08-09 | — | — | US | disclosed |
| WO-1992001700-A1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1992-02-06 | — | — | WO | disclosed |
| EP-0314011-A2 | Purine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-05-03 | — | — | EP | disclosed |