Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864496 | 0.89 | RARB (0.46) | ACACBMAPTRARBKDM4EMEN1 | |
| SCHEMBL9096988 | 0.83 | RARB (0.47) | ACACBMAPTRARBKDM4EMEN1 | |
| SCHEMBL8620927 | 0.83 | MAPT (0.40) | ACACBMAPTTHRBFFAR1FFAR4 | |
| SCHEMBL9096672 | 0.82 | RARB (0.49) | ACACBMAPTRARBKDM4EMEN1 | |
| SCHEMBL9095535 | 0.82 | RARB (0.49) | ACACBMAPTRARBKDM4EMEN1 | |
| SCHEMBL8593405 | 0.80 | CNR1 (0.38) | ACACBMMP12MAPTTHRBRARB | |
| SCHEMBL8593408 | 0.80 | CNR1 (0.38) | ACACBMMP12MAPTTHRBRARB | |
| SCHEMBL8591411 | 0.80 | RARB (0.40) | MAPTTHRBPPARARARBKDM4E | |
| SCHEMBL8594480 | 0.80 | RARB (0.40) | MAPTTHRBPPARARARBKDM4E | |
| SCHEMBL8593933 | 0.80 | RARB (0.40) | MAPTTHRBPPARARARBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537620-B1 | Nitrogen-containing heterorings | ROLIC AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| US-5326497-A | Nitrogen heterocycles and liquid crystalline mixtures containing them | HOFFMANN-LA ROCHE INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0537620-A1 | Nitrogen-containing heterorings | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |