Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864933 | 0.85 | RAB9A (0.51) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7862172 | 0.85 | RAB9A (0.51) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8620388 | 0.83 | ACACB (0.44) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8591293 | 0.82 | MEN1 (0.42) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8591279 | 0.81 | RAB9A (0.42) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7865001 | 0.79 | RAB9A (0.53) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9638283 | 0.79 | RAB9A (0.59) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9357386 | 0.79 | RAB9A (0.43) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8045876 | 0.78 | RAB9A (0.55) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8565141 | 0.78 | RAB9A (0.55) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537620-B1 | Nitrogen-containing heterorings | ROLIC AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| US-5326497-A | Nitrogen heterocycles and liquid crystalline mixtures containing them | HOFFMANN-LA ROCHE INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0537620-A1 | Nitrogen-containing heterorings | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |