Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 14/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 12/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 12/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 12/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 12/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620541 | 1.00 | GRIN1 (0.54) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8619587 | 0.82 | GRIN1 (0.54) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8619585 | 0.82 | GRIN1 (0.54) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8613818 | 0.82 | GRIN1 (0.57) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8617412 | 0.80 | GRIN1 (0.54) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8614592 | 0.79 | GRIN2D (0.51) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8614597 | 0.79 | GRIN2D (0.51) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8620906 | 0.74 | GRIN1 (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8620904 | 0.74 | GRIN1 (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL2639494 | 0.68 | GRIN2D (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837864-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | Novartis AG (CH) | 1998-04-29 | — | — | EP | claimed |
| WO-1997003079-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 1997-01-30 | — | — | WO | claimed |
| EP-0837864-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | Novartis AG (CH) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997003079-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 1997-01-30 | — | — | WO | disclosed |