Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 10/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.61 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.61 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.61 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.61 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620904 | 1.00 | GRIN1 (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8620286 | 0.85 | GRIN1 (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8620288 | 0.85 | GRIN1 (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8620550 | 0.80 | GRIN1 (0.74) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8613102 | 0.79 | GRIN2D (0.59) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8613105 | 0.79 | GRIN2D (0.59) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8619216 | 0.77 | GRIN1 (0.70) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8615504 | 0.76 | GRIN1 (0.68) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Phosphonic Acid SCHEMBL27488531 | 0.76 | GRIN1 (0.53) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8620541 | 0.74 | GRIN1 (0.54) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837864-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | Novartis AG (CH) | 1998-04-29 | — | — | EP | claimed |
| WO-1997003079-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 1997-01-30 | — | — | WO | claimed |
| EP-0837864-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | Novartis AG (CH) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997003079-A1 | NOVEL QUINOXALINE- AND QUINOXALINYLALKANE-PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 1997-01-30 | — | — | WO | disclosed |